Article

A Clinically Translatable Immune-based Classification of HPV-associated Head and Neck Cancer with Implications for Biomarker-Driven Treatment Deintensification and Immunotherapy

2022-02-27

Abstract excerpt

<h4>Purpose</h4> Human papillomavirus-associated (HPV + ) head and neck squamous cell carcinoma (HNSCC) is the fastest rising cancer in North America. There is significant interest in treatment de-escalation for these patients given the generally favourable prognosis. However, 15-30% of patients recur after primary treatment, reflecting a need for improved risk-stratification tools. We sought to develop a molecula...

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Literature Corpus work: c7a902f1-7da4-5a13-832a-9f187301c4c9
DOI: 10.1101/2022.02.26.22271531

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