Article
Novel insights into head and neck cancer using next-generation "omic" technologies.
Cancer research - 1 Feb 2015
Sepiashvili Lusia, Bruce Jeff P, Huang Shao Hui, O'Sullivan Brian, Liu Fei-Fei, Kislinger Thomas
Abstract excerpt
Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous disease that develops via one of the two primary carcinogenic routes: chemical carcinogenesis through exposure to tobacco and alcohol or virally induced tumorigenesis. Human papillomavirus (HPV)-positive (HPV(+)) and HPV-negative (HPV(-)) HNSCCs represent distinct clinical entities, with the latter associated with significantly inferior...
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