Article

From Bile Acids to a Gas-Producing Microbiome Phenotype: A Novel Mechanism of Host–Microbiome Communication

2026-09-01

Abstract excerpt

Background Microbiome-derived metabolites regulate host physiology, yet bacterial gaseous metabolites remain largely overlooked. Traditionally regarded as fermentation end-products, bacterial gases may act as biologically active mediators of host–microbiome communication. We hypothesized that bile acids regulate bacterial gaseous metabolism and influence host epithelial responses. Methods A high gas-producing clin...

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Literature Corpus work: c79f5562-305f-517b-beb4-81e7851076d6
DOI: 10.64898/2026.08.24.746699

Open publication

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