Article

Changes in Microbiota and Metabolites Are Associated With Effects of Bile Acid Sequestrant on Icteric Primary Biliary Cholangitis

2020-09-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Increasing data suggests an interaction between bile acids (BAs) and intestinal microbiota in the pathogenesis of primary biliary cholangitis (PBC). Bile acid sequestrants are widely used to bind BA in the intestinal lumen and therefore are posited to impact gut bacteria. Herein we aimed to investigate the effects of cholestyramine on the BA profile and gut microb...

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Literature Corpus work: 704fd7dd-73d8-514c-86f9-ebe7986a1ded
DOI: 10.21203/rs.3.rs-76953/v1

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