Article

Purinergic P2X7 Receptor-mediated inflammation precedes PTSD-related Behaviors in Rats

2022-03-12

Abstract excerpt

Clinical evidence has linked increased peripheral pro-inflammatory cytokines with post-traumatic stress disorder (PTSD) symptoms. However, whether inflammation contributes to or is a consequence of PTSD is still unclear. Previous research shows that stress can activate P2X7 receptors (P2X7Rs) on microglia to induce inflammation and behavioral changes. In this investigation, we examined whether P2X7Rs contribute to...

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Literature Corpus work: c7830355-b93f-5337-880c-4f97948268f1
DOI: 10.1101/2022.03.10.483788

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