Article

Medulloblastoma: From TP53 Mutations to Molecular Classification and Liquid Biopsy

2022-12-16

Abstract excerpt

A recent paradigm shift in diagnostics of medulloblastoma allows the distinction of four major groups defined by genetic data rather than histology. This new molecular classification correlates better with prognosis and will allow better clinical management for therapies targeting druggable mutations, but also offers a new combination of monitoring tumor development in real-time and treatment response by sequentia...

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Literature Corpus work: c75c38b5-7d5e-54bd-b679-bf16e5e70733
DOI: 10.20944/preprints202212.0300.v1

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