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Article

The evolution of medulloblastoma therapy to personalized medicine

2017-04-13

Abstract excerpt

Recent advances in cancer genomics have revolutionized the characterization and classification of medulloblastomas. According to the current WHO guidelines, medulloblastomas are now classified into the following molecularly defined groups: Wnt signaling pathway (WNT)-activated, sonic hedgehog signaling pathway (SHH)-activated and tumor suppressor protein p53 (TP53)-mutant, SHH-activated and TP53-wildtype, and non-...

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Literature Corpus work
3f4ceebc-1660-5166-bb57-97e0c95711f8
DOI
10.12688/f1000research.10859.1
Open publication

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