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Article

Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43

25 Apr 2023

Abstract excerpt

Congenital CMV (cCMV) infection causes neurological sequelae in newborns. Recent studies of cCMV pathogenesis in animal models reveal ventriculomegaly and cortical atrophy associated with impaired neural progenitor cell (NPC) proliferation and migration.

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Identifiers

PMID: 37097169
DOI: 10.1128/jvi.00313-23

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