Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD8+ T lymphocytes control murine cytomegalovirus replication in the central nervous system of newborn animals.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2008

Bantug Glenn R B, Cekinovic Djurdijca, Bradford Russell, Koontz Thad, Jonjic Stipan, Britt William J

Abstract excerpt

Human CMV infection of the neonatal CNS results in long-term neurologic sequelae. To define the pathogenesis of fetal human CMV CNS infections, we investigated mechanisms of virus clearance from the CNS of neonatal BALB/c mice infected with murine CMV (MCMV). Virus titers peaked in the CNS between postnatal days 10-14 and infectious virus was undetectable by postnatal day 21. Congruent with virus clearance was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Separation

Share to Central Nervous System Diseases

Share to Herpesviridae Infections

Share to Immediate-Early Proteins

Share to Monocytes

Share to Muromegalovirus

Source

Open in PubMed Open full text

Identifiers

PMID: 18641350
DOI: 10.4049/jimmunol.181.3.2111
PMCID: PMC4161464

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD8+ T lymphocytes control murine cytomegalovirus replication in the central nervous system of newborn animals.PMID 18641350Read ↗

Brain‐resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivationSemantic proximity Read ↗

Adaptive and Innate Immune Cells in Fetal Human Cytomegalovirus-Infected BrainsSemantic proximity Read ↗

Immunity to Cytomegalovirus in Early LifeSemantic proximity Read ↗

Neuropathogenesis in cytomegalovirus infection: indication of the mechanisms using mouse modelsSemantic proximity Read ↗

Limited protection against early-life cytomegalovirus infection results from deficiency of cytotoxic CD8 T cellsSemantic proximity Read ↗

Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interfaceSemantic proximity Read ↗

Cytomegalovirus Infection Impairs Immune Responses and Accentuates T-cell Pool Changes Observed in Mice with AgingSemantic proximity Read ↗

CD4 T Cells Promote CD8 T Cell Immunity at the Priming and Effector Site during Viral EncephalitisSemantic proximity Read ↗

Nonhuman Primate Models of Intrauterine Cytomegalovirus InfectionSemantic proximity Read ↗

Age determines NK cell fate and tissue compartmentalization to CMV infectionSemantic proximity Read ↗

Human Cytomegalovirus IE1 Impairs Neuronal Migration by Downregulating Connexin 43Semantic proximity Read ↗

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.