Article

Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice

2019-02-22

Abstract excerpt

<h4>Background</h4> Influenza A virus (IAV) poses threats to human health and life. Many individual studies have been carried out in mice to uncover the viral factors responsible for the virulence of IAV infections. Virus adaptation through serial lung-to-lung passaging and reverse genetic engineering and mutagenesis approaches have been widely used in the studies. Nonetheless, a single study may not provide enou...

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Literature Corpus work: c7368039-e8cd-5742-bf10-eb2c5dc7c360
DOI: 10.1101/556647

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