Article

When to wake up? The optimal waking-up strategies for starvation-induced persistence

2019-12-30

Abstract excerpt

Prolonged lag time can be induced by starvation contributing to the antibiotic tolerance of bacteria. We analyze the optimal lag time to survive and grow the iterative and stochastic application of antibiotics. A simple model shows that the optimal lag time can exhibit a discontinuous transition when the severeness of the antibiotic application, such as the probability to be exposed the antibiotic, the death rate...

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Identifiers and source

Literature Corpus work: c6bb7f32-df23-5f51-bb5a-df8be04efd24
DOI: 10.1101/2019.12.29.890285

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