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Dynamic protein aggregation regulates bacterial dormancy depth critical for antibiotic tolerance

2017-12-13

Abstract excerpt

The ability of some bacteria within a population to tolerate antibiotic treatment is often attributed to prolonged bacterial infection 1-3 . Unlike antibiotic resistance, which generally results from genetic mutations or plasmid transfer 4,5 , antibiotic tolerance usually refers to the phenomenon that a subgroup of cells can survive high dose antibiotic treatment as a result of phenotypic heterogeneity 6,7 . Pr...

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Literature Corpus work
a278d4f5-f4ce-52f5-86a0-ae06ec7c48c5
DOI
10.1101/233890
Open publication

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Dynamic protein aggregation regulates bacterial dormancy depth critical for antibiotic toleranceDOI 10.1101/233890
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