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Article

Wide lag time distributions break a trade-off between reproduction and survival in bacteria.

Proceedings of the National Academy of Sciences of the United States of America - 4 Aug 2020

Moreno-Gámez Stefany, Kiviet Daniel J, Vulin Clément, Schlegel Susan, Schlegel Kim, van Doorn G Sander, Ackermann Martin

Abstract excerpt

Many microorganisms face a fundamental trade-off between reproduction and survival: Rapid growth boosts population size but makes microorganisms sensitive to external stressors. Here, we show that starved bacteria encountering new resources can break this trade-off by evolving phenotypic heterogeneity in lag time. We quantify the distribution of single-cell lag times of populations of starved Escherichia coli and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32669426
DOI: 10.1073/pnas.2003331117
PMCID: PMC7414188

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