Article

DLG2 Impairs dsDNA Break Repair and Maintains Genome Integrity in Neuroblastoma

2021-06-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>In primary neuroblastoma, deletions on chromosome 11q are known to result in an increase in the total number of chromosomal breaks. Microhomology mediated-end joining (MMEJ) is an error-prone pathway for DNA double-strand break repair that is often upregulated in cancer. <italic>DLG2</italic>, a candidate tumor suppressor gene on chromosome 11q, has previously b...

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Literature Corpus work: c5d28721-49e9-5899-9858-cfbadc3498ac
DOI: 10.21203/rs.3.rs-549596/v1

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