Article

DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma

2021-05-05

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>In primary neuroblastoma, deletions on chromosome 11q are known to result in an increase in the total number of chromosomal breaks. Microhomology mediated-end joining (MMEJ) is an error-prone pathway for DNA double-strand break repair that is often upregulated in cancer. <italic>DLG2</italic>, a candidate tumor suppressor gene on chromosome 11q, has previously b...

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Literature Corpus work: 72d5140d-e6a7-5d92-bdda-abbcb28af4a6
DOI: 10.21203/rs.3.rs-495251/v1

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