Article

The Function of <i>Efhd1</i> <sup>+</sup> Telocytes in the Synovial Lymphatic System and Inflammatory-Erosive Arthritis

2025-11-05

Abstract excerpt

Resting collecting lymphatic vessels (cLVs) sense edema in distal joints and initiate contractions via unknown mechanisms. Rheumatoid arthritis (RA) patients have lymphatic drainage deficiencies from affected joints, and defects in the synovial lymphatic system exacerbate inflammatory-erosive arthritis in animal models. To understand this, we generated Efhd1 -CreER T2 and Myoc -CreER T2 mice for cell-specific...

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Literature Corpus work: c5d16c56-1e01-59a5-b2ca-3ed734f55f8e
DOI: 10.1101/2025.11.03.685859

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