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Reversibility of hAT-MSCs phenotypic and metabolic changes after exposure to and withdrawal form HCC-conditioned medium through regulation of the ROS/MAPK/HIF-1α signalling pathway

2020-10-28

Abstract excerpt

<h4>Background: </h4> Mesenchymal stem cells (MSCs) play an important role in tumor progression; concomitantly, MSCs also undergo profound changes in the tumor microenvironment (TME). These changes can directly impact the application and efficacy of MSC-based anti-tumor therapy. However, few studies have focused on the regulation of MSC fate in TME, which will limit the progress of MSC-based anti-tumor therapy. He...

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Literature Corpus work
c5af37e8-75e4-5413-85bd-61a04d2bd7b1
DOI
10.21203/rs.3.rs-27574/v4
Open publication

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Reversibility of hAT-MSCs phenotypic and metabolic changes after exposure to and withdrawal form HCC-conditioned medium through regulation of the ROS/MAPK/HIF-1α signalling pathwayDOI 10.21203/rs.3.rs-27574/v4
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