Article

Metabolic reprogramming and partial acquisition of cancer stem cell-like phenotype in human umbilical cord-mesenchymal stem cells under hypoxia

2026-03-13

Abstract excerpt

Mesenchymal stem cells (MSCs) cultured in hypoxic conditions have been suggested to have more therapeutic efficacy than those cultured under normoxic conditions, and there is growing interest in using hypoxic MSCs for clinical treatment, particularly human umbilical cord (hUC)-MSCs. We investigated how hUC-MSCs and human bone marrow (hBM)-MSCs change from normoxia to hypoxia (1% O 2 ) for 2 weeks of culture. In t...

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Literature Corpus work: b4e42be5-d523-59ff-9d37-09ad6798c1a3
DOI: 10.64898/2026.03.11.710925

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