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Human gut commensal <i>Alistipes timonensis</i> modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an <i>Il10</i> -deficient mouse model

2024-10-24

Abstract excerpt

Correlative studies have linked human gut microbes to specific health conditions. Alistipes is one such microbial genus negatively linked to inflammatory bowel disease (IBD). However, the protective role of Alistipes in IBD is understudied, and the underlying molecular mechanisms remain unknown. In this study, colonization of Il10 -deficient mice with Alistipes timonensis DSM 27924 delays colitis development....

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Identifiers and source

Literature Corpus work
c5ad0d97-b814-5249-9e1a-2b4d58856830
DOI
10.1101/2024.10.23.619966
Open publication

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Human gut commensal <i>Alistipes timonensis</i> modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an <i>Il10</i> -deficient mouse modelDOI 10.1101/2024.10.23.619966
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