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<i>Odoribacter splanchnicus</i> mitigates pathogen <i>-</i> induced gut inflammation and its associated pathogenesis via its secreted bacteriocin

2024-08-23

Abstract excerpt

Foodborne pathogens pose a major global health hazard, worsened by drug-resistant strains. Therefore, designing novel therapeutic strategies is crucial. Here, we identified the protective role of gut-commensal Odoribacter splanchnicus (OS) against Salmonella in mice by promoting colonization resistance, preserving gut barrier integrity, and preventing acute inflammation and biofilm formation. In vitro, both OS...

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Identifiers and source

Literature Corpus work
bf878830-7996-5352-824b-0ba1b2b72209
DOI
10.1101/2024.08.23.609322
Open publication

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