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Gut microbiota phospholipids regulate intestinal gene expression and can counteract the effects of antibiotic treatment

2025-01-28

Abstract excerpt

The gut microbiome influences immune and metabolic homeostasis. Our research using non-obese diabetic (NOD) mice revealed that early-life antibiotic exposure remodels the gut microbiome affecting metabolism and accelerating type 1 diabetes (T1D) incidence, with cecal material transplant (CMT) mitigating the damage. Now examining murine intestinal lipidomic profiles, we identified 747 compounds. Comparing the lipid...

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Literature Corpus work
a9c6e8d3-07d7-53b7-8f86-b88644196683
DOI
10.1101/2025.01.28.633906
Open publication

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Gut microbiota phospholipids regulate intestinal gene expression and can counteract the effects of antibiotic treatmentDOI 10.1101/2025.01.28.633906
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