Article

Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of <i>Akkermansia muciniphila</i> in mice

2023-06-21

Abstract excerpt

<h4>Aims</h4> Dysbiosis is an important factor that leads to metabolic disorders by disrupting energy balance and insulin sensitivity. A decrease in Akkermansia muciniphila is a phenotype of obesity-induced dysbiosis. Although interventions to increase A. muciniphila are expected to improve glucose metabolism, the underlying mechanism has not been fully understood. <h4>Methods</h4> Isoxanthohumol (IX), a pren...

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Literature Corpus work: b58b2cee-c6e6-57bd-b78c-69a3991e23f7
DOI: 10.1101/2023.06.21.543373

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