Article

Lack of consistent effect of dietary fiber on immune checkpoint blockade efficacy across diverse murine tumor models

2025-04-02

Abstract excerpt

Immune checkpoint blockade (ICB) has transformed cancer treatment, but success rates remain low in most cancers. Recent research suggest that dietary fiber enhances ICB response in melanoma patients and murine preclinical models through microbiome-dependent mechanisms. Yet, the robustness of this effect across cancer types and dietary contexts remains unclear. Specifically, prior literature compared grain-based ch...

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Literature Corpus work: c56b2e2d-9b93-5068-8ff6-508200a9ba9c
DOI: 10.1101/2025.03.28.645975

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