VIP Deficiency Increases Pro-fibrotic and Pro-inflammatory Biomarker Expression After World Trade Center Dust Exposure

Abstract excerpt

<title>Abstract</title> <p>The collapse of the World Trade Center (WTC) on September 11th, 2001 was one of the worst environmental disasters in United States history, exposing 400,000 people to a wide variety of toxicants and carcinogens. An analogous exposure, namely burn pit dust in Iraq and Afghanistan, has revealed lung injury and fibrosis in both animal and human subjects. Twenty-four years after 9/11, simil...

Topics

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• Gene Deletion
• Hypertension, Pulmonary
• Hypoxia
• Inflammation
• Mice, Knockout
• Oligonucleotide Array Sequence Analysis
• Reverse Transcriptase Polymerase Chain Reaction
• Vasoactive Intestinal Peptide

Identifiers and source

Literature Corpus work

c550f6a6-1025-576f-9676-d27506ca184a

DOI

10.21203/rs.3.rs-9431858/v1