Article

Detection of novel HIV-1 drug resistance mutations by support vector analysis of deep sequence data and experimental validation

2019-10-14

Abstract excerpt

The global HIV-1 pandemic comprises many genetically divergent subtypes. Most of our understanding of drug resistance in HIV-1 derives from subtype B, which predominates in North America and western Europe. However, about 90% of the pandemic represents non-subtype B infections. Here, we use deep sequencing to analyze HIV-1 from infected individuals in Uganda who were either treatment-naïve or who experienced virol...

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Literature Corpus work: c54f81e8-1aaa-572b-9375-f7483497fa0b
DOI: 10.1101/804781

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