Article
Comprehensive genetic analysis of adhesin proteins and their role in virulence of Candida albicans.
Genetics - 9 Feb 2021
Rosiana Sierra, Zhang Liyang, Kim Grace H, Revtovich Alexey V, Uthayakumar Deeva, Sukumaran Arjun, Geddes-McAlister Jennifer, Kirienko Natalia V, Shapiro Rebecca S
Abstract excerpt
Candida albicans is a microbial fungus that exists as a commensal member of the human microbiome and an opportunistic pathogen. Cell surface-associated adhesin proteins play a crucial role in C. albicans' ability to undergo cellular morphogenesis, develop robust biofilms, colonize, and cause infection in a host. However, a comprehensive analysis of the role and relationships between these adhesins has not been...
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