Article

Developing a whole exome sequencing-based homologous recombination deficiency test of epithelial ovarian cancer

2023-05-30

Abstract excerpt

<h4>Background: </h4> Homologous recombination deficiency (HRD) test is an important tool to stratify epithelial ovarian cancer (EOC) patients for maintenance therapy. Using whole exome sequencing (WES)-based platform can provide information of gene mutations and HRD score, however, the clinical value of WES-based HRD test was less validated in EOC. <h4>Methods:</h4> We evaluated the performance of WES-based HRD t...

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Literature Corpus work: c52239a9-c41f-5a43-99e9-c611e469a036
DOI: 10.21203/rs.3.rs-2983608/v1

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