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Article

Unanswered Questions Regarding Sex and BMP/TGF-β Signaling

2018-05-11

Abstract excerpt

Crosstalk between the BMP and TGF-β signaling pathways regulates many complex developmental processes from the earliest stages of embryogenesis throughout adult life. In many situations, the two signaling pathways act reciprocally. For example, TGF-β signaling is generally pro-fibrotic whereas BMP signaling is anti-fibrotic and pro-calcific. Sex-specific differences occur in many diseases including cardi...

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Literature Corpus work
c4e491f4-23ae-5bba-8ef4-c3423bb50ff3
DOI
10.20944/preprints201805.0180.v1
Open publication

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