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Regulators and effectors of bone morphogenetic protein signalling in the cardiovascular system

8 May 2015

Abstract excerpt

Bone morphogenetic proteins (BMPs) play key roles in the regulation of cell proliferation, differentiation and apoptosis in various tissues and organs, including the cardiovascular system. BMPs signal through both Smad-dependent and -independent cascades to exert a wide spectrum of biological activities. Cardiovascular disorders such as abnormal angiogenesis, atherosclerosis, pulmonary hypertension and cardiac...

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PMID: 25952563
DOI: 10.1113/jp270207

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