Article

Assessing the efficacy of CRISPR/Cas9 genome editing in the wheat pathogen Parastagonspora nodorum

2020-03-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The genome-editing tool CRISPR/Cas9 has revolutionized gene manipulation by providing an efficient method to generate targeted mutations. This technique deploys the Cas9 endonuclease and a guide RNA (sgRNA) which interact to form a Cas9-sgRNA complex that initiates gene editing through the introduction of double stranded DNA breaks. We tested the efficacy of the...

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Literature Corpus work: c4d36114-9d68-546e-b9a7-6ded7bf5d77a
DOI: 10.21203/rs.2.23248/v2

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