Article

Gene and metabolite expression dependence on body mass index in human myocardium

2021-07-03

Abstract excerpt

We hypothesized that body mass index (BMI) dependent changes in myocardial gene expression and energy-related metabolites underlie the biphasic association between BMI and mortality (the obesity paradox) in cardiac surgery. We performed transcriptome profiling and measured a panel of 144 metabolites in 53 and 55, respectively, myocardial biopsies from a cohort of sixty-seven adult patients undergoing coronary arte...

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Literature Corpus work: c4aaeaa4-1fbf-5bc9-b01d-2290da83941c
DOI: 10.1101/2021.06.29.21259697

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