Back to search

Article

Microarray, validation and gene-enrichment approach for assessing differentially expressed circulating miRNAs in obese and lean heart failure patients

2025-02-18

Abstract excerpt

<h4>Background</h4> Obesity is a risk factor associated with cardiovascular diseases that may lead to heart failure (HF). However, in HF, overweight and obese patients have longer survival than underweight patients, a phenomenon known as the obesity paradox. MiRNAs play a fundamental role in gene regulation and transcription factors involved in obesity and HF. The main objective of this study was to identify and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
606b301e-5a1e-53c0-87f5-167aafcbdf76
DOI
10.1101/2025.02.15.638475
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Microarray, validation and gene-enrichment approach for assessing differentially expressed circulating miRNAs in obese and lean heart failure patientsDOI 10.1101/2025.02.15.638475
Circulating microRNAs in obese and lean heart failure patients: A case–control study with computational target prediction analysisSemantic proximity
RNA sequencing and bioinformatics analysis of tissue biopsy of abdominal fat in obesity associated with cardio-metabolic diseasesSemantic proximity
Transcriptome profiling reveals novel BMI- and sex-specific gene expression signatures for human cardiac hypertrophySemantic proximity
Potential diagnostic value of circulating miRNAs in HFrEF and bioinformatics analysisSemantic proximity
Identification of Molecular Signatures in Epicardial Adipose Tissue in Heart Failure with Preserved Ejection FractionSemantic proximity
Noncoding and Coding Mechanisms of Aging Heart Failure with Preserved Ejection Fraction with Thyroid DysfunctionSemantic proximity
Expression profiles and functional analysis of tRNA-derived small RNAs in epicardial adipose tissue of patients with heart failureSemantic proximity
Unveiling miRNA Biomarkers for Hypertrophic Cardiomyopathy through Integrated Bioinformatics and Machine Learning AnalysisSemantic proximity
MicroRNAs in Obesity-Associated Disorders: The Role of Exercise TrainingSemantic proximity
Whole-genome transcriptomic insights into protective molecular mechanisms in metabolically healthy obese African AmericansSemantic proximity
Obesity/cardiometabolic phenotype of heart failure with preserved ejection fraction: mechanisms to recent trials.Semantic proximity
Expression and correlation of circulating miRNAs in healthy obese childrenSemantic proximity
Select a neighboring publication to make it the new centre.