Article
Genetic Polymorphisms of Tumor Necrosis Factor Alpha and Susceptibility to Dengue Virus Infection in a Mexican Population.
Viral immunology - 1 Oct 2017
Sánchez-Leyva Marina, Sánchez-Zazueta Jorge Guillermo, Osuna-Ramos Juan Fidel, Rendón-Aguilar Horacio, Félix-Espinoza Rafael, Becerra-Loaiza Denisse Stephania, Sánchez-García Dulce Carolina, Romero-Quintana José Geovanni, Castillo Ureta Hipolito, Velarde-Rodríguez Ismael, Velarde-Félix Jesús Salvador
Abstract excerpt
To evaluate the association of the -308 and -238 tumor necrosis factor alpha (TNF-α) gene polymorphisms with clinical manifestations of dengue and TNF-α serum levels in a northwestern Mexican population. The study populations included dengue fever (DF) and dengue hemorrhagic fever (DHF) patients, and a group of healthy controls (HCs) without history of dengue. Polymerase chain reaction-restriction fragment length...
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