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A Triple-Action Nanoplatform for Retinal Neovascularization: Penetrating Ocular Barriers, Blocking Angiogenesis and Fibrosis, and Restoring Mitophagy

2026-08-19

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Retinal neovascularization remains a leading cause of visual loss in retinal disorders, with key pathological features including endothelial cell overgrowth, ROS-driven fibrosis, and alterations in the extracellular matrix. YAP1, a transcription factor that regulates both cell proliferation and fibrotic responses, has emerged as an attractive target for inte...

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Literature Corpus work
c48aab2b-ce23-5f17-8f1c-bec70ee582cc
DOI
10.21203/rs.3.rs-10597858/v1
Open publication

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A Triple-Action Nanoplatform for Retinal Neovascularization: Penetrating Ocular Barriers, Blocking Angiogenesis and Fibrosis, and Restoring MitophagyDOI 10.21203/rs.3.rs-10597858/v1
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