Article

Polydopamine Nanoparticles Attenuate Retina Ganglion Cell Degeneration and Restore Visual Function After Optic Nerve Injury

2021-10-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Oxidative stress contributes to retina ganglion cells (RGCs) loss in variety of ocular diseases, including ocular trauma, ocular vein occlusion, and glaucoma. Scavenging the excessed reactive oxygen species (ROS) in retinal neurovascular unit could be beneficial to RGCs survival. In this study, a polydopamine (PDA)-based nanoplatform is developed to protect RGCs...

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Literature Corpus work: 58f1cc7c-d982-5399-9ae4-7b8656906ecc
DOI: 10.21203/rs.3.rs-940186/v1

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