Article

Streptolysin production and activity is central to <i>in vivo</i> pathotype and disease outcome in GAS infections

2019-06-28

Abstract excerpt

Streptococcus pyogenes (GAS) is among the most diverse of all human pathogens, responsible for a range of clinical manifestations, from mild superficial infections such as pharyngitis to serious invasive infections such as necrotising fasciitis and sepsis. The drivers of these different disease phenotypes are not known. The GAS cholesterol-dependent cytolysin, streptolysin O (SLO), has well established cell and ti...

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Literature Corpus work: c46b5c88-76f4-5334-8ad4-c73a344b5fb2
DOI: 10.1101/686303

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