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The <i>Streptococcus agalactiae</i> LytSR two-component regulatory system promotes vaginal colonisation and virulence <i>in vivo</i>

2024-08-02

Abstract excerpt

Streptococcus agalactiae (or Group B Streptococcus , GBS) is a leading cause of neonatal sepsis and meningitis globally. To sense and respond to variations in its environment, GBS possesses multiple two-component regulatory systems (TCSs) such as LytSR. Here, we aimed to investigate the role of LytSR in GBS pathogenicity. We generated an isogenic lytS knockout mutant in a clinical GBS isolate and used a combinat...

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Identifiers and source

Literature Corpus work
bff768e8-112e-5ca7-a44a-a34e83863952
DOI
10.1101/2024.08.02.606384
Open publication

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