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TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG

2021-04-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Neuronal death is a major hallmark of Alzheimer’s disease (AD). Necroptosis, as a programmed necrotic process, is activated in AD. However, what signals and factors initiate necroptosis in AD is basically unknown. <bold>Methods </bold>We examined the expression levels of critical molecules in necroptotic signaling pathway by immunohistochemistry (IHC) staining an...

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Literature Corpus work: c3f29509-b979-5e49-b329-61ea69b26b44
DOI: 10.21203/rs.3.rs-425226/v1

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