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Necroptosis and Alzheimer’s Disease: Pathogenic Mechanisms and Therapeutic Opportunities

28 Nov 2022

Abstract excerpt

Alzheimer's disease (AD) is considered to be the most common neurodegenerative disease, with clinical symptoms encompassing progressive memory loss and cognitive impairment. Necroptosis is a form of programmed necrosis that promotes cell death and neuroinflammation, which further mediates the pathogenesis of several neurodegenerative diseases, especially AD. Current evidence has strongly suggested that...

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PMID: 36463451
DOI: 10.3233/jad-220809

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