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Western diet unmasks transient low-level vinyl chloride exposure-induced tumorigenesis; potential role of the (epi-)transcriptome

2022-02-25

Abstract excerpt

<h4>Background & Aims</h4> Vinyl chloride (VC) monomer is a volatile organic compound commonly used in industry to produce polyvinyl chloride (PVC). At high exposure levels, VC causes liver cancer and toxicant-associated steatohepatitis. However, lower exposure levels (i.e., < regulatory exposure limits) that do not directly damage the liver, enhance injury caused by Western diet (WD). Although these lower exposu...

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Literature Corpus work
c3c4d378-6262-5519-9419-7679d6116f49
DOI
10.1101/2022.02.24.481808
Open publication

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Western diet unmasks transient low-level vinyl chloride exposure-induced tumorigenesis; potential role of the (epi-)transcriptomeDOI 10.1101/2022.02.24.481808
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