Article

Single Cell lineage Tracing Identifies Cancer Testis Antigens as Mediators of Chemoresistance in Small Cell Lung Cancer

2022-10-21

Abstract excerpt

Small Cell Lung Cancer (SCLC) is often a heterogeneous tumor, where dynamic regulation of key transcription factors can drive multiple populations of phenotypically different cells which contribute differentially to tumor dynamics. This tumor is characterized by a very low 2-year survival rate, high rates of metastasis, and rapid acquisition of chemoresistance. The heterogeneous nature of this tumor makes it diffi...

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Literature Corpus work: c3ac1fa8-0713-5f5c-b3ed-18d243bd7c25
DOI: 10.1101/2022.10.20.513051

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