Article

Systematic analysis of IL-1 cytokine signaling by high-risk HPV oncoproteins

2022-08-26

Abstract excerpt

<h4>ABSTRACT</h4> Human papillomavirus (HPV) E6 and E7 oncoproteins are expressed at all stages of HPV-mediated carcinogenesis and are essential drivers of cancers caused by high-risk HPV. Some of the activities of HPV E6 and E7, such as their interactions with host cellular tumor suppressors, have been characterized extensively. There is less information about how high-risk HPV E6 and E7 alter cellular responses...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7e64a897-44f7-5a1b-8863-b4968e502ffd
DOI: 10.1101/2022.08.25.505364

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Systematic analysis of IL-1 cytokine signaling by high-risk HPV oncoproteinsDOI 10.1101/2022.08.25.505364Read

Modulation of microRNA-mRNA Target Pairs by Human Papillomavirus 16 OncoproteinsSemantic proximity Read

What are the essential determinants of human papillomavirus carcinogenesis?Semantic proximity Read

Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicitySemantic proximity Read

The Epithelial Immune Response to Human Papillomavirus InfectionSemantic proximity Read

The role of inflammation in HPV carcinogenesisSemantic proximity Read

Advances in understanding the mechanisms of the human papillomavirus oncoproteinsSemantic proximity Read

Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesSemantic proximity Read

Molecular Insights into HPV-Driven Cervical Cancer: Oncoproteins, Immune Evasion, and Epigenetic ModificationsSemantic proximity Read

The Human Papillomavirus (HPV) E1 protein regulates the expression of cellular genes involved in immune responseSemantic proximity Read

Comparative Analysis of Alpha and Beta HPV E6 Oncoproteins: Insights into Functional Distinctions and Divergent Mechanisms of PathogenesisSemantic proximity Read

Alteration of the IFN-Pathway by Human Papillomavirus Proteins: Antiviral Immune Response Evasion MechanismSemantic proximity Read

Molecular Insights into HPV-Driven Head and Neck Cancers: From Viral Oncoproteins to Precision TherapeuticsSemantic proximity Read