Article

Targeting individual cells by barcode in pooled sequence libraries

2017-08-20

Abstract excerpt

There is rising interest in applying single-cell transcriptome analysis and other single-cell sequencing methods to resolve differences between cells. Pooled processing of thousands of single cells is now routinely practiced by introducing cell-specific DNA barcodes early in cell processing protocols 1-5 . However, researchers must sequence a large number of cells to sample rare subpopulations 6-8 , even when fl...

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Literature Corpus work: c36a2b06-b8d5-5910-9419-23ade06034cc
DOI: 10.1101/178681

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