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Single-cell RNA-Seq reveals the link between <i>CD45</i> isoforms and tumor-infiltrating T cells heterogeneity in liver cancer

2020-03-25

Abstract excerpt

CD45 isoforms play a major role in characterizing T cell function, phenotype, and development. However, there is lacking comprehensive interrogation about the relationship between CD45 isoforms and T lymphocytes from cancer patients at the single-cell level yet. Here, we investigated the CD45 isoforms component of published 5,063 T cells of hepatocellular carcinoma (HCC), which has been assigned functional states...

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Literature Corpus work
c36214cb-acbc-5f11-8b58-e1547f6c2058
DOI
10.1101/2020.03.22.002824
Open publication

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Single-cell RNA-Seq reveals the link between <i>CD45</i> isoforms and tumor-infiltrating T cells heterogeneity in liver cancerDOI 10.1101/2020.03.22.002824
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