Article

An IL-34–IGF-1 inflammatory axis fuels KRAS-mutant lung cancer progression

2026-07-15

Abstract excerpt

Macrophages are innate immune cells of embryonic or adult origin with tissue specific roles in homeostasis, disease surveillance, and wound repair that can be co-opted to promote tumor growth and spread 1–11 . An understanding of the specific roles of macrophage subsets in lung tumor initiation and progression could promote new therapeutic approaches for this deadly disease. Here, we show that KRAS G12D mutation...

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Literature Corpus work: c348beb6-d3d1-5d5f-8cd5-6dd6b1d11e41
DOI: 10.64898/2026.07.14.738492

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