Article

High incidence of AZF duplications in clan-structured Iranian populations detected through Y chromosome sequencing read depth analysis

2023-06-02

Abstract excerpt

The ampliconic region of the human Y chromosome consists of large duplicated sequences that can undergo non-allelic homologous recombination (NAHR), resulting in structural rearrangements that may cause infertility, especially when they occur in the azoospermia factor b/c (AZFb/c) region. Although AZF duplications have long been neglected due to the technical limitations of STS-based studies that focused mainly on...

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Literature Corpus work: c316bd77-8290-5c08-a16e-67a0b931168a
DOI: 10.21203/rs.3.rs-2966401/v1

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