Article
Inferring post-transcriptional regulation within and across cell types in human testis
2024-10-13
Abstract excerpt
Single-cell tissue atlases commonly use RNA abundances as surrogates for protein abundances. Yet, protein abundance also depends on the regulation of protein synthesis and degradation rates. To estimate the contributions of such post transcriptional regulation, we quantified the proteomes of 5,883 single cells from human testis using 3 distinct mass spectrometry methods (SCoPE2, pSCoPE, and plexDIA). To distinguis...
Topics
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- Advanced Proteomics Techniques and Applications
- Ferroptosis and cancer prognosis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
- Sexual Differentiation and Disorders
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- c2af64b6-154d-5001-b9a2-0992332b6cfe
- DOI
- 10.1101/2024.10.08.617313
