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Escherichia coli Promotes Myofibroblast Differentiation in Urethral Fibrosis Urethral Stricture in vivo and vitro via regulating TGFβ/Smad Signaling Pathway

2025-09-03

Abstract excerpt

<title>Abstract</title> <p> Urethral stricture in children is a challenging condition to treat, with a high rate of postoperative recurrence. Previous studies based on 16S rRNA and transcriptomic analyses have suggested a positive correlation between urethral stricture and <italic>Escherichia coli</italic> (E. coli), as well as the transforming growth factor-β (TGF-β)/Smad signaling pathway. Notably, even <it...

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Literature Corpus work: c264bf90-5a21-52b1-9179-604824fa9323
DOI: 10.21203/rs.3.rs-6821103/v1

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