Article

Attenuated crosstalk between urothelium and fibroblasts promotes ureteral stricture development Urothelial-Fibroblast Crosstalk in Stricture

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>Background Ureteral stricture (US), characterized by fibrotic remodeling of the ureteral wall, represents an obstructive urological disorder with incompletely characterized pathophysiological mechanisms. This study integrates single-cell RNA sequencing (scRNA-seq) with immunohistochemical validation in human tissues to investigate the molecular and cellular mechanisms underlying US path...

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Literature Corpus work: c8169a23-1876-5f53-867b-9410a6ee147a
DOI: 10.21203/rs.3.rs-7276176/v1

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