Article

Synthetic RNA-protein decoy granules to prevent SARS-CoV-2 infection

2026-01-19

Abstract excerpt

<h4>Summary</h4> Synthetic receptor decoys offer a promising strategy to block viral entry but are often limited by instability and rapid clearance. Here we introduce AntiCoV decoy particles: phase-separated synthetic RNA-protein nanoparticles that display multivalent human ACE2 and act as robust decoy receptors for SARS-CoV-2. The granules remain structurally stable for at least two weeks at room temperature. Us...

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Literature Corpus work: c241b2d0-4679-5afe-a0b9-73ad5eb2f0a3
DOI: 10.64898/2026.01.16.699918

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